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Cognitive and Sensory Imaging Laboratory

Real-Time Imaging

The overarching goals of the Cognitive and Sensory Imaging (CASI) Laboratory are to understand the interactions between sensory experience and higher-order cognition such as working memory and executive function throughout the lifespan, and to characterize what these interactions look like in the brain.

The lab uses multiple techniques to determine the complex interactions between sensory experience, neural function and behavior. Studies use:

  • State-of-the-art brain imaging, including magnetoencephalography (MEG) and structural and functional MRI
  • Comprehensive behavioral testing
  • Advanced audiometric and sensory measurements.

We are particularly interested in clarifying the impact of mild-to-severe hearing loss and the quality of therapeutic interventions (e.g., hearing aid use and audibility) on the neural dynamics that serve cognitive development in children and adolescents. There is high variability in behavioral outcomes in these children. Some children with hearing loss perform at or above their normal-hearing peers on tests of cognition and language, while others fall persistently behind.

Real-time Imaging

We hope that by studying the neural dynamics affecting these cognitive processes in real-time (rather than depending on end-point behavioral metrics) we will be able to uncover the root of this range of outcomes. The results of these studies may lead to better-informed, individualized therapies for children with hearing loss.



Our Studies

Developmental Changes in the Brain and Their Link to Psychiatric Traits
The aim of this study is to use brain functional imaging results to understand the brain changes related to puberty and how they can lead to the onset of psychiatric disorders.
Investigating the Neural Dynamics Serving Working Memory in Children with ADHD
This project is an extension of study 1 and aims to further characterize the age-related changes seen in healthy and clinical populations of youth, particularly in those with attention-deficit/hyperactivity disorder.
Characterizing the Impact of Hearing Loss on Cognitive and Neural Function in Children and Adolescents
This project seeks to provide new data on the impact of hearing loss and hearing aid measures on cognitive, language and neural function in children ages 7-15.
Spatiotemporal Dynamics of Language Processing in School-Age Children with Mild-to-Severe Hearing Loss
This project aims to further characterize the associations between auditory access, language processing, and neural development in a large cohort of children with hearing loss and demographically matched normal hearing children.

Meet Our Staff

Elizabeth Heinrichs-Graham, Ph.D.
Director, Cognitive and Sensory Imaging Laboratory
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